Louisville (pronounced LEW-iss-vill) is a city in Winston County, Mississippi. The population was 7,006 at the 2000 census. It is the county seat of Winston County.
The American Heritage "Big Red" Fire Museum is located in Louisville. This museum features a collection of restored antique fire equipment and fire engines. The Strand Theatre, in downtown Louisville, is an historic movie theater which now serves as an art and music venue. Louisville native Carl Jackson plays an annual Christmas concert at the theater to raise money for the building's restoration
Mississippi Highway 14 enters east from the Alabama state line through Macon and when it enters in Louisville it is also known as Main Street. It leaves westbound eventually traveling to the Mississippi River where it ends.
Mississippi Highway 15 enters from the north from Ackerman, MS, then meets up with Mississippi Highway 25 just north of Louisville. M.S. 25 enters from the north from Starkville. M.S. 15 and 25 travel together along the western side of town. At the southern edge of town they separate: M.S. 15 traveling to Philadelphia & Interstate 20; and M.S. 25 to Jackson.